Protein Structure Laboratory
University of Kansas
Structural Biology Center
2121 Simons Drive, Room 115
Lawrence, KS 66047

Office and Laboratory: (785) 864-3772
Fax: (785) 864-5326

High brilliance X-ray generator, Xtream 2000, and the new Raxis IV++ imaging plate available at the Protein Structure Laboratory offer a complete system for single crystal diffraction data acquisition.

The Structural Biology Center (SBC), shown
above, houses the COBRE's Protein Structure Laboratory, it's Protein Purification
Laboratory, and related laboratories of KU's Molecular Structures Group.

The mission of the Protein Structure Laboratory (PSL) is to provide investigators with state-of-the-art instrumentation, facilities, and expertise for protein crystallization, X-ray data collection, data analysis, and structure solution and refinement from an a la carte menu.

The PSL staff will perform or assist investigators with any of these functions:

• Crystallization of an investigator’s target proteins
• Collection of complete X-ray diffraction data sets locally and at synchrotron
• Phase determination (experimentally or through molecular replacement)
• Model building and refinement of structures deduced from diffraction data
• Publications and grant applications involving X-ray crystallographic issues

For more information about the PSL:

• Protein Crystallography Primer
• PSL Brochure
• PSL Fees
• Work Request Form

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