How should I credit NCRR and NIGMS in my publications?

Publications and Invited Presentations

COBRE-PSF Publications, 2002-2012

2012

DeVore, N.M., Scott, E.E. (2012) Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001. Nature. 482(7383):116-9.

Devore NM, Meneely KM, Bart AG, Stephens ES, Battaile KP, Scott EE. (2012) Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. FEBS J. 279(9):1621-31.

Bann, J.G. (2012) Anthrax toxin protective antigen: Insights into molecular switching from prepore to pore. (2012) Protein Sci. 21(1): DOI: 10.1002/pro.752. PMCID: PMC3323776

Takahashi, D., Kim, Y., Chang, K.O., Anbanandam, A., Prakash, O. (2012) Backbone and side-chain ¹H, ¹5N, and ¹³C resonance assignments of Norwalk virus protease. Biomol NMR Assign. 6(1):19-21. Epub 2011 Jun 8.

2011

Priyadarshi, A., Tang, L. (2011) Crystallization and preliminary crystallographic analysis of the type III secretion translocator chaperone SicA from Salmonella enterica, Acta Crystal. Sect F; Structural Biology and Crystallization Communications F66: 1533-1535.

Andra, K.K., Bullinger, J.C., Bann, J.G., Eichhorn, D.M. (2011) 2-Fluoro-I-histidine. Acta Cyrstallogr. Sect. E. Struct. Rep. 66(Pt. 11):o2713.

Parthasarathy, S. Altuve, A., Terzyan, S., Zhang, X.-J., Kuczera, D., Rivera, M., Benson, D.R. (2011) Accommodating a non conservative internal mutation by water-mediated hydropgen bonding between beta-sheet strands: A comparison of human and rat type B (mitochondrial) cytochrome beta-five. Biochemistry 50: 5544-5554.

An, C., Lovell, S.W., Kanost, M.R., Battaile, K.P., Michel, K. (2011) Crystal structure of native Anopheles gambiae Serpin-2, a negative regulator of melanization in mosquitoes, Proteins, 1999-2003.

Hickey, J.M., Weldon, L., Hefty, P.S. (2011) The Atypical OmpR/PhoB Response Regulator ChxR from Chlamydia trachomatis Forms Homodimers In Vivo and Binds a Direct Repeat of Nucleotide Sequences. J. Bacteriol. 193(2):389-98. PMID21057008; PMC3019824

Hickey, J.M., Lovell, S., Battaile, K.P., Hu, L., Middaugh, C.R., Hefty, P.S. (2011) The atypical response regulator protein ChxR has structural characteristics and dimer interface interactions that are unqiue within the OmpR/PhoB subfamily. J. Biol. Chem. 2011 286(37): 32606-16.

Panja, A., Campana, C., Leavitt, C., Van Stipdonk, M.J., and Eichhorn, D.M. (2011) Iron and cobalt complexes of 2,6-diacetylpyridine-bis(R-thiosemicarbazone) (R+H, phenyl) showing unprecedented ligand deviation from planarity, Inorganica Chim Acta, 362(4): 1348-1354.

Park, K.-T., Wu, W., Battaile, K.P., Lovell, S.W., Holyoak, T., Lutkenhaus, J. (2011) The min oscillator uses mind-dependent conformational changes in mine to spatially regulate cytokinesis. Cell 146: 396-407.

Wu, W., Park, K.-T., Holyoak, T., Lutkenhaus, J., (2011) Determination of the structure of the MinD-ATP complex reveals the orientaiton of MinD on the membrane and the relative location of the binding sites for MinE and Min C. Molecular Microbiolog 79 (6): 1515-1528.

Yao, H., Jepkorir, G., Lovell, S.W., Nama, P.V., Weeratunga, S., Battaile, K.P., Rivera, M. (2011) Two distinct ferritin-like molecules in Pseudomonas aeruginosa: The product of the bfrA gene is a bacterial ferritin (FtnA) and not a bacterioferritin (Bfr). Biochemistry 50: 5236-5248.

An, C., Budd, A., Kanost, M.R., Michel, K. (2011) Characterization of a regulatory unit that controls melanization and affects longevity of mosquitoes. Cell. Mol. Life Sci. 68: 1929-1939.

Estrada, D.F., De Guzman, R.N. (2011) Structural characterization of the Crimean-Congo hemorrhagic fever virus GN tail provides insight into virus assembly. J. Biol. Chem. 286 (24): 21678-28686.

Lee, S. Y.-C., De La Mota-Peynado A., Roelofs, J. (2011) Loss of Rpt5 interactions with the core particle and Nas2 causes the formation of faulty proteasomes that are inhibited by Ecm29. J. Biol. Chem. 286 (42): 36641-36651.

Lee, K.I., Jo, S., Rui, H., Egworlf, B., Roux, B., Pastor, R.W., Im, W. (2011) Web interface for brownian dynamics simulation ion transport and its applications to beta-barrel pores. J. Comp. Chem.DOI: 10.1002/jcc.21952. (331-339).

Jo, S., Song, K.C., Desaire, H., MacKerell, Jr., A.D., Im, W. (2011) Glycan Reader: Automated sugar identification and simulation preparation for carbohydates and glycoproteins. 32(14): 3135-3141.

Cruz, P.G., Auld, D.S., Schultz, P.J., Lovell, S.W., Battaile, K.P., MacAuthur, R., Shen, M., Tamayo-Castillo, G., Ingelese, J., Sherman, D.H. (2011) Titration-based screening for evaluation of natural product extracts: Identification of an aspulvinone family of Luciferase inhibitors. Chem & Biol. 18: 1442-1452.

Kemege, K.E., Hickey, J.M., Lovell, S., Battaile, K.P., Zhang, Y., Hefty, P.S. (2011) Ab Initio structural modeling of and expereimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes. J. Bacteriology 193(23): 6517-6528. DOI: 10.1128/JB.05488-11.

Chatterjee S., Zhong, D., Nordhues, B.A., Battaile, K.P., Lovell, S., De Guzman, R.N. (2011) The crystal structures of the Salmonella type II secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate. Protein Sci. 20(1): 75-86.

Malik, S.S., Rich,E., Viswanathan, R., Cairns B.R., Fischer, C.J. (2011) Allosteric interactions of DNA and nucleotides with S. cerevisiae RSC. Biochemistry. 50(37):7881-90.

Timothy P. Day Diptesh Sil Nikunj M. Shukla Asokan Anbanandam Victor W. Day and Sunil A. David. (2011) Imbuing Aqueous Solubility to Amphotericin B and Nystatin with a Vitamin.
molecular pharmaceutics Mol. Pharm. 8(1): 297-301.

Zimmerman, J.R., Smucker, B.W., Dain, R.P., Van Stipdonk, M.J., Eichhorn, D.M. (2011) Tridentate N(2)S ligand from 2,2'-dithiodibenzaldehyde and N,N-dimethylethylenediamine: Synthesis, structure, and charactierziation of a Ni(II) complex with relevance to Ni Superoxide Dismutase. Inorganica Chim Acta. 373(1): 54-61.

Nti-Addae, K.W., Laurence, J.S., Skinner, A.L., Stella, V.J. (2011) .Reversion of sulfenamide prodrugs in the presence of free thiol-containing proteins. J Pharm Sci. 100(7):3023-7. doi: 10.1002/jps.22505. Epub 2011 Feb 3.

2010

Xia, Z., Chibnik, L.B., Glanz, B.I., Liguori, M., Shulman, J.M., Tran, D., Khoury, S.J., Chitnis, T., Holyoak, T., Weiner, H.L., Guttmann, C.R.G., De Jager, P.L. (2010) A putative Alzheimer’s Disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. ;5(11):e14169. PMID: 21152065

Auld, D.S., Lovell, S., Thorne, N., Lea, W.A., Maloney, D.J., Shen, M., Rai, G., Battaile, K.P., Thomas, C.J., Simeonov, A., Hanzlik, R.P., Inglese, J. (2010) Molecular basis for the high-affinity binding and stabilization of fireflyluciferase by PTC124.Proc Natl Acad Sci U S A. 107(11):4878-83. PMID20194791; PMC2841876

Deng, B., Parthasarathy, S., Wang, W., Gibney, B.R., Battaile, K.P., Lovell, S., Benson, D,R., Zhu, H. (2010) Study of the individual cytochrome b5 and cytochrome b5 reductase domains ofNcb5or reveals a unique heme pocket and a possible role of the CS domain.J Biol Chem. 285(39):30181-91. PMID20630863; PMC2943328

Fenton, A.W., Johnson, T.A., Holyoak, T. (2010) The pyruvate kinase model system, a cautionary tale for the use of osmolyteperturbations to support conformational equilibria in allostery. Protein Sci. 19(9):1796-800. PMID20629175; PMC2975142

Jepkorir, G., Rodriguez, J.C., Rui, H., Im, W., Lovell, S., Battaile, K.P., Alontaga, A.Y.,Yukl E.T., Moanne-Loccoz, P., Rivera, M. (2010) Structural, NMR spectroscopic, and computational investigation of hemin loading in thehemophore HasAp from Pseudomonas aeruginosa. J. Am. Chem. Soc. 132(28):9857-72. PMID20572666; PMC2948407

Jiang, L., Fang, J., Moore, D.S., Gogichaeva, N.V., Galeva, N.A., Michaelis, M.L., Zaidi, A. (2010) Age-associated changes in synaptic lipid raft proteins revealed by two-dimensional fluorescence difference gel electrophoresis.Neurobiol Aging. 31(12):2146-59. PMID19118924; PMC2904836

Johnson, T.A., Holyoak, T. (2010) Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalyticfidelity. Biochemistry. 49(25):5176-87. PMID20476774; PMC2893389

Khaki, A.R., Field, C., Malik, S., Niedziela-Majka, A., Leavitt, S.A., Wang, R., Hung, M., Sakowicz, R., Brendza, K.M., Fischer, C.J. (2010) The macroscopic rate of nucleicacid translocation by hepatitis C virushelicase NS3h is dependent on both sugar and base moieties.J Mol Biol. 400(3):354-78. PMID20451531; PMC2902667

Matlock, D.L., Yeruva, L., Byrd, A.K., Mackintosh, S.G., Langston, C., Brown, C., Cameron, C.E., Fischer, C.J., Raney, K.D. (2010) Investigation of translocation, DNA unwinding, and protein displacement byNS3h, the helicase domain from the hepatitis C virus helicase. Biochemistry. 49(10):2097-109. PMID20108974; PMC2853022

Mueller, A.K., Kohlhepp, F., Hammerschmidt, C., Michel, K. (2010) Invasion of mosquito salivary glands by malaria parasites: prerequisites anddefense strategies.Int J Parasitol. 40(11):1229-35. PMID20621627; PMC2916662

Porubsky, P.R., Battaile, K.P., Scott, E.E. (2010) Human cytochrome P450 2E1 structures with fatty acid analogs reveal apreviously unobserved binding mode.J Biol Chem. 285(29):22282-90. PMID20463018; PMC2903405

Rathinavelan, T., Tang, C., De Guzman, R.N. (2010) Characterization of the interaction between the Salmonella type III secretionsystem tip protein SipD and the needle protein PrgI by paramagnetic relaxation enhancement. J Biol Chem. PMID21138848

Rathinavelan, T., Zhang, L., Picking, W.L., Weis, D.D., De Guzman, R.N., Im, W. (2010) A repulsive electrostatic mechanism for protein export through the type III secretion apparatus.Biophys J. 98(3):452-61. PMID20141759; PMC2814197

Reed, T., Lushington, G.H., Xia, Y., Hirakawa, H., Travis, D.M., Mure, M., Scott, E.E., Limburg, J. (2010) Crystal structure of histamine dehydrogenase from Nocardioides simplex.J Biol Chem. 285(33):25782-91. PMID20538584; PMC2919140

Tomko, E.J., Fischer, C.J., Lohman, T.M. (2010) Ensemble methods for monitoring enzyme translocation along single strandednucleic acids.Methods. 51(3):269-76. PMID20371288; PMC2900532

Weeratunga, S.K., Lovell, S., Yao, H., Battaile, K.P., Fischer, C.J., Gee, C.E., Rivera, M. (2010) Structural studies of bacterioferritin B from Pseudomonas aeruginosa suggest agating mechanism for iron uptake via the ferroxidase center .Biochemistry. 49(6):1160-75. PMID20067302; PMC2852880

Wimalasena, D.S., Janowiak, B.E., Lovell, S., Miyagi, M., Sun, J., Zhou, H., Hajduch, J., Pooput, C., Kirk, K.L., Battaile, K.P., Bann, J.G. (2010) Evidence that histidine protonation of receptor-bound anthrax protectiveantigen is a trigger for pore formation.Biochemistry. 49(33):6973-83. PMID20672855; PMC2924283

Zhao, H., Finch, C.J., Sequeira, R.D., Johnson, B.A., Johnson, J.E., Casjens, S.R., Tang, L. (2010) Crystal structure of the DNA-recognition component of the bacterial virus Sf6genome-packaging machine. Proc. Natl. Acad. Sci. U S A. 107(5):1971-6.

2009

Carlson, G.M., Holyoak, T. (2009) Structural insights into the mechanism of phosphoenolpyruvate carboxykinase catalysis. J. Biol. Chem. 284 (40): 27037-41

Hickey, J.M., Hefty, P.S., Lamb, A.L. (2009) Expression, purification, crystallization and preliminary X-ray analysis of theDNA-binding domain of a Chlamydia trachomatis OmpR/PhoB-subfamily responseregulator homolog, ChxR. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65(Pt 8): 791-4.

Johnson, T.A., Qiu, J., Plaut, A.G., Holyoak, T. (2009) Active-site gating regulates 0036 substrate selectivity in a chymotrypsin-likeserine protease the structure of haemophilus influenzae immunoglobulin A1protease. J. Mol. Biol. 389(3): 559-74.

Meneely, K.M., Barr, E.W., Bollinger, J.M. Jr, Lamb, A.L. (2009) Kinetic mechanism of ornithine hydroxylase (PvdA) from Pseudomonas aeruginosa: substrate triggering of O2 addition but not flavin reduction. Biochemistry 48 (20): 4371-6

Rajapaksha, M., Eichler, J.F., Hajduch, J., Anderson, D.E., Kirk, K.L., Bann, J.G. (2009) Monitoring anthrax toxin receptor dissociation from the protective antigen by NMR. Protein Sci. 18 (1):17-23

Rui, H., Lee, J., Im, W. (2009) Comparative molecular dynamics simulation studies of protegrin-1 monomer anddimer in two different lipid bilayers.Biophys. J. 97(3):787-95.

Skinner, A.L., Laurence, J.S. (2009) 1H, 15N, 13C resonance assignments of the reduced and active form of human Protein Tyrosine Phosphatase, PRL-1. Biomol. NMR Assign. 3(1):61-5

Skinner, A.L., Vartia, A.A., Williams, T.D., Laurence, J.S. (2009) Enzyme activity of phosphatase of regenerating liver is controlled by the redox environment and its C-terminal residues. Biochemistry 48 (20): 4262-72

Weeratunga, S.K., Gee, C.E., Lovell, S., Zeng, Y., Woodin, C.L., Rivera, M. (2009) Binding of Pseudomonas aeruginosa apobacterioferritin-associated ferredoxin to bacterioferritin B promotes heme mediation of electron delivery and mobilization of core mineral iron. Biochemistry 48 (31): 7420-31

Williams, A.S., Lovell, S., Anbanandam, A., El-Chami, R., Bann, J.G. (2009) Domain 4 of the anthrax protective antigen maintains structure and binding to the host receptor CMG2 at low pH. Protein Sci. 18 (11):2277-86

Zaidi, A., Fernandes, D., Bean, J.L., Michaelis, M.L. (2009) Effects of paraquat-induced 0001 oxidative stress on the neuronal plasma membraneCa(2+)-ATPase. Free Radic. Biol. Med. 47(10):1507-14.

Zhao, H., Heroux, A., Sequeira, R.D., Tang, L. (2009) Preliminary crystallographic studies of the regulatory domain of responseregulator YycF from an essential two-component signal transduction system. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65(Pt 7):719-22.

Zhao, H., Tang, L. (2009) Crystallographic characterization of a multidomain histidine protein kinasefrom an essential two-component regulatory system. Acta Crystallogr. Sect. F Struct Biol. Cryst. Commun. 65(Pt 4):346-9.

Fischer, C.J., Yamada, K., Fitzgerald, D.M. (2009) Kinetic mechanism for single-stranded DNA binding and translocation by Saccharomyces cerevisiae Isw2. Biochemistry 48(13): 2960-8. PMID: 19203228

Katayama, H., McGill, M., Kearns, A., Brzozowski, M., Degner, N., Harnett, B., Kornilayev, B., Matkovic-Calogovic D., Holyoak, T., Calvet, J.P., Gogol, E.P., Seed, J., Fisher, M.T. (2009) Strategies for folding of affinity tagged proteins using GroEL and osmolytes. J. Struct. Funct. Genomics 10:57-66. PMID: 19082872

Thomas, C.A., Talaty, E.R., Bann, J.G. (2009) 3S-fluoroproline as a probe to monitor proline isomerization during protein folding by 19F-NMR. Chem. Communications (Camb). 23: 3366-68. PMID: 19503872

Johnson, T.A., Qiu, J., Plaut, A.G., and Holyoak, T., Active-site gating regulates substrate selectivity in a chymotrypsin-like serine protease the structure of haemophilus influenzae immunoglobulin A1 protease. J. Mol. Biol. 2009, 389(3):559-74. PMID: 19393662

Ciaccio, N.A., and Laurence, J.S., Effects of disulfide bond formation and protein helicity on the aggregation of activating transcription factor 5. Mol. Pharm. (2009) May 28. PMID: 19435374

Skinner, A.L., Vartia, A.A., Williams, T.D., Laurence, J.S. Enzyme activity of phosphatase of regenerating liver is controlled by the redox environment and its C-terminal residues. Biochemistry (2009) 48(20):4262-72. PMID: 19341304

Swint-Kruse, L., Matthews, K.S., Allostery in the LacI/GalR family: variations on a theme.
Curr. Opin. Microbiol. (2009) 12(2):129-37. PMID: 19269243

2008

De Guzman, R.N., Bacterial nanoinjectors, Chemical Biology (Royal Society 0037
of Chemistry), 2008, 3, B81-B88.

Chen, X.W., Han, B., Fang, J., Haasl, R.J., Large-scale Protein-Protein Interaction prediction using novel kernel methods. Int. J. Data Min Bioinform. 2008, 2(2): 145-56. PMID18767352

Ciaccio, N.A., Moreno, M.L., Bauer, R.L., Laurence, J.S., High-yield expression in E. coli and refolding of
the bZIP domain of activating transcription factor 5. Protein Expr. Purif. 2008, 62: 235-43. PMID18718539 PMC2599749

Lee, J., Chen, J., Brooks, C.L. 3rd, Im, W. Application of solid-state NMR restraint potentials in membrane protein modeling. J. Magn. Reson. 2008, 193(1):68-76.

Martin, A., David, V., Laurence, J.S., Schwarz, P,M., Lafer, E.M., Hedge, A.-M., Rowe, P.S. Degradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP. Endocrinology, 2008, 149(4): 1757-72. PMID18162525 PMC2276704

Meinhardt, S., Swint-Kruse, L., Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: bioinformatics-based predictions generate true positives and false
negatives. Proteins, 2008, 73(4): 941-57. PMID18536016 PMC2585155

Miller, M.A., Scott, E.E., Limburg, J., Expression, purification, crystallization and preliminary X-ray studies of a prolyl-4-hydroxylase protein from Bacillus anthracis. Acta Crystallogr. Sect.
F Struct. Biol. Cryst. Commun. 2008, 64(9): 788-91. PMID18765905 PMC2531266

Porubsky, P.R., Meneely, K.M., Scott, E.E. Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. J. Biol. Chem. 2008, 283(48): 33698-707. PMID18818195 PMC2586265

Rajapaksha, M., Eichler, J.F., Hajduch, J., Anderson, D.E., Kirk, K.L., and Bann, J.G., Monitoring Anthrax toxin receptor dissociation from the protective antigen by NMR. Protein Science. 2008,18: 17-23. 10.1002/pro.26.

Reed, T.M., Hirakawa, H., Mure, M., Scott, E.E., Limburg, J., Expression, purification, crystallization and
preliminary X-ray studies of histamine dehydrogenase from Nocardioides simplex. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2008, 64(9): 785-7 PMID18765904 PMC2531280

Rodriguez, J.C., Zeng, Y., Wilks, A., Rivera, M., The hydrogen-bonding network in heme oxygenase also functions as a modulator of enzyme dynamics: chaotic motions upon disrupting the H-bond network in heme oxygenase from Pseudomonas aeruginosa. J. Am. Chem. Soc. 2007, 129(38): 11730-42. PMID17764179

Schlicht, K.E., Michno, N., Smith, B.D., Scott, E.E., Murphy, S.E., Functional characterization of CYP2A13 polymorphisms. Xenobiotica, 2007, 37: 1439-49. PMID17922361

Skinner, A.L., Laurence, J.S., High-field solution NMR spectroscopy as a tool for assessing protein interactions with small molecule ligands. J. Pharm. Sci., 2008, 97: 4670-95 PMID18351634

Swint-Kruse, L., Fisher, H.F., Enzymatic reaction sequences as coupled multiple traces on a multidimensional landscape. Trends Biochem. Sci. 2008, 33: 104-12. PMID18261912

Taraban, M., Zhan, H., Whitten, A.E., Langley, D.B., Matthews, K.S., Swint-Kruse, L., Trewhella, J., Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein. J. Mol. Biol. 2008, 376(2): 466-81. PMID18164724 PMC2430094

Tarca, A.L., Carey, V.J., Chen, X.-W., Romero, R.R., Sorin, S., Machine learning and its applications to biology. PLoS Comput. Biol. 2007 3(6): e116. PMID17604446 PMC1904382

Wang, Y., Zhang, L., Picking, W.L., Picking, W.D., De Guzman, R.N., Structural dissection of the extracellular moieties of the type III secretion apparatus. Molecular BioSystems, 2008, 4: 1176-1180.

Wang, Y., Ouellette, A.N., Egan, C.W., Rathinavelan, T., Im, W., De Guzman, R.N., Differences in the electrostatic surfaces of the type III secretion needle proteins PrgI, BsaL, and MxiH. J. Mol. Biol. 2007, 371(5): 1304-14 PMID17617421 PMC1976599

Zhan, H., Taraban, M., Trewhella, J., Swint-Kruse, L., Subdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved
residues in a LacI/GalR homologue. Biochemistry, 2008, 47(31): 8058-69. PMID18616293 PMC2561905

Panja, A., Campana, C., Leavitt, C., Van Stipdonk, M.J., and Eichhorn, D.M., Iron and cobalt complexes of 2,6-diacetylpyridine-bis(R-thiosemicarbazone) (R=H, phenyl) showing unprecedented ligand deviation from planarity, Inorg. Chim. Acta. 2008, accepted for publication.

Swint-Kruse, L., Fisher, H.F., Enzymatic reactions sequences as coupled multiple traces on a multidimensional landscape, Trends in Biochem. Sci.. 2008, 33(3): 104-112. PMID: 18261912

Taraban, M., Zhan, H., Whitten, A.E., Langley, D.B., Matthews, K.S., Swint-Kruse L., Trewhella, J., Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein, J. Mol. Biol. 2008, 376(2): 466-81. PMID: 18164724

Bousfield, G.R., Butnev, V.Y., Bidart, J.M., Dalpathado, D., Irungu, J., and Desaire, H., Chromatofocusing fails to separate hFSH isoforms on the basis of glycan structure. Biochemistry2008 , 47(6):1708-20.

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2007

Taraban, M., Zhan, H., Matthews, K., Swint-Kruse, L., Trewhella, J., Small angle scattering studies of Lacl repressor. Biophysical J. Supplement 2007, 52a: 238-Pos.

Swint-Kruse, L., Zhan, H., Tungtur, A., Meinhardt, S., Functional effects of exchanging domains between homologous proteins are mediated by the linker. Biophysical J. Supplement 2007, 219a: 1027-Pos.

Irungu, J., Go, E.P., Dalpathado, D.S., Desaire, H., Simplification of mass spectral analysis of acidic glycopeptides using GlycoPep ID. Anal. Chem. 2007, 79(8):3065-74. PMID: 17348632

Go, E.P., Rebecchi, K.R., Dalpathado, D.S., Bandu, M.L., Zhang, Y., Desaire, H., GlycoPep DB: a tool for glycopeptide analysis using a "Smart Search". Anal. Chem. 2007, 79(4):1708-13. PMID: 17297977

Kolin, A., Jevtic, V., Swint-Kruse, L., Egan S. M., Linker regions of the RhaS and RhaR proteins. J. Bacteriology 2007, 189(1): 269-271. PMID: 17071764

Tungtur, S., Egan, S.M., Swint-Kruse, L., Functional consequences of exchanging domains between LacI and PurR are mediated by the intervening linker sequence. Proteins: Structure, Function, and Bioinformatics 2007, 68(1):375-88. PMID: 17436321

Stubbs, J.R., Liu, S., Tang, W, Zhou, J., Wang, Y., Yao, X., Quarles, D.L., Role of hyperphosphatemia and 1,25(OH)2D in vascular calcification and mortality in fibroblastic growth factor 23 null mice. J. Am. Soc. Nephrol. 2007, 18(7): 2116-24. PMID: 17554146

Liu, S., Quarles, L.D., How fibroblast growth factor 23 work. J. Am. Soc. Nephrol. 2007, 18(6): 1637-1647. (Review) PMID: 17494882

Liu, S., Gupta, A., Quarles, D.L., Emerging role of fibroblast growth factor 23 in a bone-kidney axis regulating systemic phosphate homeostasis and extracellular matrix mineralization. Curr. Opin. Nephrol. Hypertens. 2007, 16(4):329-35. (Review) PMID: 17565275

Liu, S., Rowe, P.S., Vierthaler, L., Zhou, J., Quarles, L.D., Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity. J. Endocrinol. 2007, 192(1):261-7. PMID: 17210763

Smith, B.D., Sanders, J.L., Porubsky, P.R., Lushington, G.H., Stout, C.D., Scott, E.E., Structure of the human lung cytochrome P450 2A13. J. Biol. Chem. 2007, 282: 17306 - 17313. PMID: 17428784 doi:10.1074/jbc.M702361200

Wilson, C.J., Zhan, H.L., Swint-Kruse, L., Matthews, K.S., Ligand interactions with Lac repressor protein and the repressor-operator complex: The effects of ionization and oligomerization on binding. Biophys. Chem. 2007, 126: 94-105. PMID: 16860458

Wilson, C.J., Zhan, H.L., Swint-Kruse, L., Matthews, K.S., The lactose repressor system: Paradigms for regulation, allosteric behavior, and protein folding. Cell. Mol. Life Sci. 2007, 64: 3-16. PMID: 17103112

Birket, S., Harrington, A.T., Espina, M., Smith, N., Terry, C.M., Darboe, N., Markham, A.P., Middaugh, C.R., Picking, W.L., Middaugh, C.R., Picking, W.D., Preparation and characterization of rranslocator/chaperone complexes and their component proteins from Shigella flexneri. Biochemistry 2007, 46(27): 8128 - 8137. PMID: 17571858

Johnson, S., Roversi, P., Espina, M., Olive, A., Deane, J.E., Birket, S., Field, T., Picking, W.D., Blocker, A.J., Galyov E.E., Picking, W.L., Lea, S.M., Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD. J. Biol. Chem. 2007, 282 (6): 4035-44. PMID: 17077085

Wickstrum, J. R., Kolin, A.D., Jin, J., Fang, J., Egan, S.M., Transcription activation by the DNA-binding domain of the AraC family protein RhaS in the absence of its effector-binding domain, J. Bacteriol. 2007, 189(14): 4984-93. PMID: 17513476

Ansar, S., Burlison, J.A., Hadden, M.K., Yu, X.M., Desino, K.E., Bean, J., Neckers, L., Audus, K.L., Michaelis, M.L., and Blagg, B.S., A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity. Bioorg. Med. Chem. Lett. 2007, 17(7):1984-90. PMID: 17276679

Imormino, R.M., Blagg, B.S.J., Gewirth, D.T., Inhibitory ligands adopt different conformations when bound to Hsp90 or GRP94: Implications for paralog-specific drug design. J. Med. Chem. 2007, in press.

Bishop, S., Burlison, J., Blagg, B.S.J., Hsp90: A novel target for the disruption of multiple signaling cascades. Invited Review for Current Cancer Drug Targets2007, in press.

Tarca, A., Carey, V., Chen, X.-W., Romero, R., Draghici, S., Machine learning and its applications to biology. PLoS Computational Biology 2007, in press.

Chen, X.-W, Han, B., Fang, J., Haasl, R., Large-scale protein-protein interaction prediction using novel kernel methods. International Journal of Data Mining and Bioinformatics 2007, in press.

Stubbs, J.R., Liu, S., Quarles, D.L., Role of fibroblast growth factor 23 (FGF23) in phosphate homeostasis and pathogenesis of disordered mineral metabolism in chronic kidney disease. Semin. Dialysis. 2007, 20(4):302-8. PMID: 17635819 [PubMed - in process]

Schlicht, K.E., Michno, N., Smith, B.D., Scott, E.E., and Murphy, S.E., Functional characterization of CYP2A13 polymorphisms, Xenobiotica 2007, in press.

Meinhardt, S., Swint-Kruse, L., Amino acid substitutions at nonconserved positions modify function in transcription repressors engineered from LacI and GalR. J. Mol. Biol. 2007, in press.

Wang, Y., Quellette, A.N., Egan, C.W., Rathinavelan, T., Im, W., De Guzman, R.N., Differences in the electrostatic surfaces of the type III secretion needle proteins PrgI, BsaL, and MxiH. J. Mol. Biol. 2007, 371(5):1304-14. Epub 2007 Jun 15. PMID: 17617421 [PubMed - in process]

Zhang, L., Wang, Y., Olive, A.J., Smith, N.D., Picking, W.D., De Guzman, R.N., Picking, W.L., Identification of the MxiH needle protein residues responsible for anchoring IpaD to the type III secretion needle tip. J. Biol. Chem. 2007, Sep 7; [Epub ahead of print] PMID: 17827155

Smucker, B.W., Van Stipdonk, M.J., Eichhorn, D.M., Incorporation of thiolate donation using 2,2'-Dithiodibenzaldehyde: Complexes of a pentadentate N2S3 ligand with relevance to the active site of co nitrile hydratase, J. Inorg. Biochem.2007, 101(10):1537-42. Epub 2007 Aug 14. PMID: 17698201

Kim, D.-Y., Calvert, J.G., Chang, K.-O., Holren, K., Kerrigan, M., Rowland, R.R.R., Expression and stability of foreign tags inserted into nsp2 of porcine reproductive and respiratory syndorome virus (PRRSV). Virus Res. 2007, 128(1-2):106-14. Epub 2007 Jun 5. PMID: 17553585 [PubMed - in process]

Martin, A., David, V., Laurence, J.S., Schwarz, P.M., Lafer, E.M., Hedge, A.M, Rowe, P.S., Coordination of a metal ligand by the C-terminus of PRL-1 regulates its phosphatase activity. Endocrinology 2008, 149(4):1757-72. PMID: 18162525

Rodriquez, J.C., Zeng, Y., Wilks, A., Rivera, M., The hydrogen bonding network in heme oxygenase also functions as a modulator of enzyme dynamics: Chaotic motions upon disrupting the H-bond network in heme oxygenase from Pseudomonas aeruginosa, J. Am. Chem. Soc. 2007, 129(38):11730-42.. PMID: 17764179

Bann, J.G., Wimalasena, S., Cramer, J., Kirk, K., Anderson, D., Collier, R., Melnyk, R., Juris, S., Janowiak, B., Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation and translocation, Biochemistry, 2007, 46(51):14928-36. PMID: 18044973

Meneely, K.M., Lamb, A.L., Biochemical characterization of a flavin adenine dinucleotide-dependent monooxygenase, ornithine hydroxylase from Pseudomonas aeruginosa, suggests a novel reaction mechanism. Biochemistry 2007, 46(42):11930-7. PMID: 17900176

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2006

Avila, C., Hadden, M.K., Ma, Z., Kornilayev, B.A., Ye, Q.Z., Blagg, B.S.J., High-throughput screening for Hsp90 ATPase inhibitors. Bioorg. Med. Chem. Lett. 2006, 16(11): 3005-8. PMID: 16530412

Wang, M., Shen, G., Blagg, B.S.J., Radanamycin, a macrocyclic chimera of radicicol and geldanamycin. Bioorg. Med. Chem. Lett. 2006, 16(9): 2459-62. PMID: 16464590

Blagg, B.S.J., Kerr, T.D., Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation. Med. Res. Rev. 2006, 26(3): 310-38. PMID: 16385472

Avila, C., Kornilayev, B.A., Blagg, B.S.J., Development and optimization of a useful assay for determining Hsp90's inherent ATPase activity. Bioorg. Med. Chem. 2006, 14(4):1134-42. PMID: 16213144

Shen, G., Wang, M., Welch, T.R., Blagg, B.S.J., Design, synthesis, and structure--activity relationships for chimeric inhibitors of Hsp90. J. Org. Chem. 2006, 71(20):7618-31. PMID: 16995666

Peng, W., Blagg , B.S.J., A versatile approach toward the ansamycin antibiotics. Org. Lett. 2006, 8(5): 975-8. PMID: 16494488

Bousfield, G.R., Jia, L., Ward, D.N., Gonadotropins: Chemistry and Biosynthesis. In: Neill J.D. (ed) Knobil and Neill: Physiology of Reproduction, 3rd Edition, Elsevier Press, San Diego, CA, 2006, pp. 1581-1634.

Zhang, L., Wang, Y., Picking, W.L., Picking, W.D., De Guzman, R.N., Solution structure of monomeric BsaL, the type III secretion needle protein of Burkholderia pseudomallei. J. Mol. Biol. 2006, 359(2): 322-30. PMID: 16631790

Bandu, M.L., Desaire, H., The STEP method (Statistical Test of Equivalent Pathways): Application to pharmaceuticals. Analyst 2006, 131: 268-274 (Invited submission). PMID: 16440093

Huang, M., Xie, S.-X., Ma, Z.-Q., Hanzlik, R.P., Ye, Q.Z., Metal mediated inhibition of methionine aminopeptidase by quinolinylsulfonamides. Biochem. Biophys. Res. Commun. 2006, 339: 506 13. PMID: 16300729

Irungu, J., Dalpathado, D.S., Go, E.P., Jiang, H., Ha, H.V., Bousfield, G.R., Desaire, H., Method for characterizing sulfated glycoproteins in a glycosylation site-specific fashion, using ion-pairing and tandem mass spectrometry. Anal. Chem. 2006, 78: 1181-1190. PMID: 16478110

Zaitseva, J., Lu, J., Olechoski, K.L., Lamb, A.L., Two crystal structures of the isochorismate pyruvate lyase from Pseudomonas aeruginosa. J. Biol. Chem. 2006, 281(44): 33441-9. PMID: 16914555

Darboe, N., Kenjale, R., Picking, W.L., Picking, W.D., Middaugh, C.R., Chemical denaturation of MxiH from Shigella and PrgI from Salmonella. Prot. Sci. 2006, 15(3): 543-52. PMID: 16501225

Deane, J.E., Cordes, F.S., Roversi, P., Johnson, S., Kenjale, R., Picking, W.D., Picking, W.L., Lea, S.M., Blocker, A., Expression, purification, crystallization and preliminary crystallographic analysis of MxiH, the subunit of the Shigella flexneri type III secretion system. Acta Crystallogr. (Sect. F Struct. Biol. Cryst. Commun.) 2006, 62: 302-305. PMID: 16511329

Zhan, H., Swint-Kruse, L., Matthews, K.S., Extrinsic interactions dominate helical propensity in coupled binding and folding of lactose repressor protein hinge helix. Biochemistry 2006, 45: 5896-5906. (Designated as “Hot Article” by Biochemistry editors.) PMID: 16669632

Haasl, R.J., Fang, J.W., Mining protein-protein interaction data. Current Bioinformatics 2006, 1-2: 197-205.

Fang, J.W., Dong, Y.H., Lushington, G.H., Ye, Q.Z., Georg, G.I., Support vector machines in HTS data mining: Type I MetAPs inhibition study. J. Biomolecular Screening 2006, 11(2): 138-144. PMID: 16418315

Xie, S.X., Huang, W.J., Ma, Z.Q., Huang, M., Hanzlik, R.P., Ye, Q.Z., Structural analysis of metalloform-selective inhibition of methionine aminopeptidase. Acta Crystallogr. D Biol. Crystallogr. 2006, 62(4): 425-32. PMID: 16552144

Feng, J.Q., Ward, L. M., Liu S., Lu, Y., Xie, Y., Yuan, B., Yu, X., Rauch, F., Davis, S.I, Zhang, S., Rios, H., Drezner, M.K., Quarles, L.D., Bonewald, L.F., White, K.E., Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat. Genet. 2006, 38(11): 1310-5. PMID: 17033621 http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17033621

Liu, S., Zhou, J., Tang, W., Jiang, X., Rowe, D.W., Quarles, L.D., Pathogenic role of FGF23 in Hyp mice. Am. J. Physiol. Endocrinol. Metab. 2006, 291(1): E38-49. PMID: 16449303

Liu, S., Tang, W., Zhou, J., Stubbs, J.R., Luo, Q., Pi, M., Quarles, L.D., FGF23 is a counter-regulatory phosphaturic hormone for vitamin D. J. Am. Soc. Nephrol. 2006, 17(5): 1305-1315. PMID: 16597685

Rowe, P.S., Matsumoto, N., Jo, O.D., Shih, R.N., O’Connor, J., Roudier, M.P., Bain, S., Liu, S., Harrison, J., Yanagawa, N., Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin. Bone 2006, 39(4): 773-786. PMID: 16762607

Liu, S., Lu, Y., Xie, Y., Zhou, J., Bondwald, L.F., Quarles, L.D., Feng, J.Q., Elevated levels of fgf23 in dentin matrix protein 1 (Dmp1) null mice potentially explain phenotypic similarities to hyp mice. The 28th Annual Meeting of the American Society of Bone and Mineral Research, Philadelphia, PA. September 2006. J. Bone Miner. Res. 2006, 21 (suppl1): S51, 1191.

Liu, S., Tang, W., Zhou, J., Quarles, L.D., Local osteoblast/osteocyte defect in Hyp mice causes overproduction of fgf23. The 28th Annual Meeting of the American Society of Bone and Mineral Research, Philadelphia, PA. September 2006. J. Bone Miner. Res. 2006, 21 (suppl1): S51, 1192.

Liu, S., Rowe, P.S.N., Vierthaler, L., Zhou, J., Quarles, L.D., Phosphorylated ASARM peptide from MEPE stimulates FGF23 transcription by inhibiting PHEX enzyme activity. ASN Renal Week 2006, San Diego, CA, November 2006. Abstract F-SA-DS532. J. Am. Soc. Nephrol. 2006, 17:687A.

Stubbs J., Liu S., Tang W., Quarles, L.D., Role of hyperphosphatemia and 1,25(OH)2D3 in vascular calcifications and mortality in FGF23 Null Mice. ASN Renal Week 2006, San Diego, CA, November 2006. Abstract SA-PO541. J. Am. Soc. Nephrol. 2006, 17:689A.

Xie, L., Boyle, D., Sanford, D., Scherer, P.E., Pessin, J.E., Mora, S., Intracellular trafficking and secretion of adiponectin is dependent of GGA coated vesicles. J. Biol. Chem. 2006, 281: 7253-7259. PMID: 16407204

Gupte, A., Mora, S., Activation of the Cbl insulin signaling pathway in cardiac muscle; Dysregulation in obesity and diabetes. Biochemical and Biophysical Research Communications 2006, 342(3):751-757. PMID: 16494846

Wu, D., Asiedu, M., Adelstein, R.S., Wei, Q., A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis. Cell Cycle 2006, 5(11): 1234-1239. PMID: 16721066

Galeva, N.A., Jiang, L., Zaidi, A., Michaelis, M.L., Williams, T.D., Processing ESI-MSI data obtained on a Q-TOF mass spectrometer to improve the results of protein analysis. Proceedings of the American Society for Mass Spectrometry, 2006.

Hadden, M.K., Lubbers, D., Blagg, B.S.J., Geldanamycin, radicicol, and chimeric inhibitors of the Hsp90 N-terminal ATP binding site. Curr. Topics Med. Chem.2006, 6(11):1173-82. PMID: 16842154

Harrington, A.T., Darboe, N., Kenjale, R., Picking, W.L., Middaugh, C.R., Birket, S., Picking, W.D., Characterization of the interaction of single tryptophan containing mutants of IpaC from Shigella flexneri with phospholipid membranes. Biochemistry 2006, 45: 626-636. PMID: 16401091

Dalpathado, D.S., Irungu, J., Go, E.P., Nortan, K., Bousfield, G.R., Desaire, H., Comparative glycomics of the glycoprotein Follicle-Stimulating Hormone (FSH): Glycopeptide analysis of isolates from two mammalian species. Biochemistry 2006, 45(28): 8665-8673. PMID: 16834341

Zhang, Y., Jiang, H., Go, E.P., Desaire, H., Distinguishing phosphorylation and sulfation in carbohydrates and glycoproteins using ion-pairing and mass spectrometry. J. Am. Soc. Mass Spectrom. 2006, 17(9): 1282-88. PMID: 16820302

Fang, Y., Pekosz, A., Haynes, L., Nelson, E.A., Rowland, R.R.R., Production and characterization of monoclonal antibodies against the nucleocapsid protein of Sars-CoV. Adv. Exp. Med. Biol. 2006, 581: 153-156. PMID: 17037523

Ding, X., Lichti, K., Kim I., Gonzalez, F.J, Staudinger, J.L., Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha. J. Biol. Chem. 2006, 281 (36): 26540-51. PMID: 16825189

Johnson, S., Roversi, P., Espina, M., Deane, J.E., Birket, S., Picking, W.D., Blocker, A., Picking, W.L., Lea, S.M., Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. 2006, 62(9): 865-8. PMID: 16946465

Staudinger, J.L., Ding, X., Lichti, K., Pregnane X receptor and natural products: Beyond drug-drug interactions. Expert Opin. Drug Metab. Toxicol. 2006 Dec, 2(6):847-857. PMID: 17125405

Yamada, T.T., Komoto, J.J., Saiki, K.K., Konishi, K.K. Takusagawa, F.F., Variation of loop sequence alters stability of cytolethal distending toxin (CDT): Crystal structure of CDT from Actinobacillus actinomycetemcomitans. Protein Sci. 2006, 14(2): 362-372. PMID: 16434747

Blagg, B.S.J., Targeting the Hsp90-mediated protein folding machinery for the treatment of cancer and neurodegenerative diseases. Proceedings of the National IDeA Symposium of Biomedical Research Excellence 2006, #PP360, C330. (COBRE)

Ding, X., Kim, I., Gonzalez, F.J., Staudinger, J.L., Regulation of constitutive androstane receptor and its target genes by fasting, cyclic AMP, hepatocyte nuclear factor 4-alpha and the peroxisome proliferator-activated receptor-gamma-coactivator-protein-1alpha. Proceedings of the National IDeA Symposium of Biomedical Research Excellence 2006, #PP175, C38.

Pham, A.L., Fu, Q., Zolkiewski, M., Bann, J.G., Initial characterization of CooB: A chaperone protein involved in the assembly of CS1 pili. Proceedings of the National IDeA Symposium of Biomedical Research Excellence 2006, #PP289, C286-287.

Duzhak, T., Kornilayev, B., Huang, W., Yamamoto, Y., Kansas COBRE in Protein Structure and Function: From cloning to crystallization through core labs, Proceedings of the National IDeA Symposium of Biomedical Research Excellence 2006, #C3, C2-3.

Smith, B.D., Sanders, J.L., Stout, C.D., Scott, E.E., Structure and function of the human lung cytochrome P450 2A13, principle activator of the major nicotine-derived procarcinogen. Proceedings of the National IDeA Symposium of Biomedical Research Excellence 2006, #PP085, C164.

Smith, B.D., Sanders, J.L., Stout, C.D., Scott, E.E., Human cytochrome P450 2A13: Correlation between a 2.35Å structure and ligand binding, Experimental Biology 2006, San Francisco, CA, FASEB J. 2006, 18: LB511 Suppl.

Zaidi, A., Jiang L, Bean, J.L., Michaelis, M.L., Age-dependent decrease in synaptic membrane Ca2+-ATPase occurs selectively in cholesterol rich microdomains. Proceedings of the National IDeA Symposium of Biomedical Research Excellence 2006, #PP 419, C371.

Fernandes, D., Zaidi, A., Bean, J.L., Michaelis, M.L., RNAi-induced silencing of the plasma membrane Ca2+-ATPase 2 increase the vulnerability of neurons to stimuli that alter intracellular calcium. Free Radical Biology and Medicine 2006, 41: S169.

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2005

Yu, X.M., Shen, G., Neckers, L., Blake, H., Holzbeierlein, J., Cronk, B., Blagg, B.S., Hsp90 inhibitors identified from a library of novobiocin analogues. J. Am. Chem. Soc. 2005, 127(37): 12778-9. PMID: 16159253

Yu, X.M., Han, H., Blagg, B.S., Synthesis of mono- and dihydroxylated furanoses, pyranoses, and an oxepanose for the preparation of natural product analogue libraries. J. Org. Chem. 2005, 70(14): 5599-605. PMID: 15989342

Shen, G., Blagg, B.S., Radester, a novel inhibitor of the Hsp90 protein folding machinery. Org. Lett. 2005, 7(11): 2157-60. PMID: 15901158

Harvey, D.J., Bousfield, G.R., Differentiation between sulphated and phosphated carbohydrates in low-resolution matrix-assisted laser desorption/ionization mass spectra. Rapid Commun. Mass Spectrom. 2005, 19(2): 287-8. PMID: 15609366

Desaire, H., Mass Spectrometry (Carbohydrate analysis). 2005 Yearbook of Science and Technology. McGraw-Hill, New York, pp. 197-200, 2005.

Jiang, H., Irungu, J., Desaire, H., Enhanced detection of sulfated glycosylation sites in glycoproteins. J. Am. Soc. Mass Spectrom. 2005, 16: 340-348. PMID: 15734327

Dalpathado, D.S., Jiang, H., Kater, M.A., Desaire, H., Reductive amination of carbohydrates using NaBH(OAc)3. Anal. Bioanal. Chem. 2005, 381: 1130-1137. PMID: 15761738

Zhang, Y., Go, E.P., Jiang, H., Desaire, H., A novel mass spectrometric method to distinguish isobaric compounds that are phosphorylated or sulfated using ion-pairing reagents. J. Am. Soc. Mass Spectrom. 2005, 16(11): 1827-1839. PMID: 16185888

Bandu, M.L., Wilson, J., Vachet, R.W., Dalpathado, D.S., Desaire, H., STEP Analysis (Statistical Test of Equivalent Pathways): A new mass spectrometric method for carbohydrates and peptides. Anal. Chem. 2005, 77: 5886-5893. PMID: 16159118

Wickstrum, J.R., Santangelo, T.J., Egan, S.M., Cyclic AMP receptor protein and RhaR synergistically activate transcription from the L-rhamnose-responsive rhaSR promoter in Escherichia coli. J. Bacteriol. 2005, 187(19): 6708-18. PMID: 16166533

Picking, W.L., Nishroka, H., Hearn, P.D., Blocker, A., Baxter, M.A., Picking, W.D., Structure-function analysis of invasion plasmid antigen D (IpaD) from Shigella flexneri. Infect. Immun. 2005, 73: 1432-1440. PMID: 15731041

Kenjale, R., Wilson, J., Zenk, S.F., Saurya, S., Picking, W.L., Picking, W., Blocker, A., The needle component of the type III secreton of Shigella regulates the activity of the secretion apparatus. J. Biol. Chem. 2005, 280: 42929-42937. PMID: 16227202

Cordes, F., Daniell, S., Kenjale, R., Saurya, S., Picking, W.L., Picking, W.D., Booy, F., Lea, S., Blocker, A., Helical packing of needles from functionally altered Shigella type III secretion systems. J. Mol. Biol. 2005, 354: 206-211. PMID: 16243352

Ding, X., Staudinger, J.L., The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter. J. Pharmacol. Exp. Ther. 2005, 314(1): 120-7. PMID: 15833898

Ding, X., Staudinger, J.L., Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase. C. Biochem. Pharmacol. 2005, 69(5): 867-73. PMID: 15710363

Ding, X., Staudinger, J.L., Induction of drug metabolism by Forskolin: The role of the pregnane X receptor and the protein kinase a signal transduction pathway. J. Pharmacol. Exp. Ther. 2005, 312(2): 849-56. PMID: 15459237

Yi, H., Gruszczynska-Biegala, J., Wood, D., Zhao, Z., Zolkiewska, A., Cooperation of the metalloprotease, disintegrin, and cysteine-rich domains of ADAM12 during inhibition of myogenic differentiation. J. Biol. Chem. 2005, 280: 23475-23483. PMID: 15849365 http://www.jbc.org/cgi/reprint/280/25/23475

Zhao, Z., Gruszczynska-Biegala, J., Zolkiewska, A., ADP-ribosylation of integrin a7 modulates the binding of integrin a7b1 to laminin. Biochem. J. 2005, 385: 309-317. PMID: 15361073 http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=15361073

Chen, X.-W., Liu, M., Prediction of protein-protein interactions using random decision forest framework. Bioinformatics 2005, 21: 4394-4000. PMID: 16234318 http://bioinformatics.oxfordjournals.org/cgi/reprint/21/24/4394

Marchin, M., Kelly, P.T., Fang, J.W., Tracker: continuous HMMER and BLAST searching. Bioinformatics 2005, 21: 388-389. PMID: 15347577 http://bioinformatics.oxfordjournals.org/cgi/reprint/21/3/388

Gangani, R. A., Silva, D., Hilliard, G.H., Fang, J.W., Macha, S., Davidson, W.S. A three dimensional molecular model of lipid-free apolipoprotein A-I determined by cross-linking/mass spectrometry and sequence threading, Biochemistry 2005, 44: 2759-2769. PMID: 15723520

Fang, J.W., Haasl, R.J., Dong, Y.H., Lushington, G.H., Discover protein sequence signatures from protein-protein interaction data. BMC Bioinformatics 2005, 6: 277. PMID: 16305745 http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16305745

Wang, L., Liu, S., Quarles, L.D., Spurney, R.F., Targeted overexpression of G protein-coupled receptor kinase 2 (GRK2) in osteoblasts promotes bone loss. Am. J. Physiol. Endocrinol. Metab. 2005, 288(4): E826-34. PMID: 15585587

Liu, S., Brown, T.A., Zhou, J., Xiao, Z., Awad, H.A., Guilak, F., Quarles, L.D., Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia. J. Am. Soc. Nephrol. 2005, 16(6): 1645-53. PMID: 15843468

Xiao, Z., Awad, H.A., Liu, S., Mahlios, J., Zhang, S., Guilak, F., Mayo, M.S., Quarles, L.D., Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice. Dev. Biol. 2005, 283(2): 345-56. PMID: 15936013

Wu, W.H., Fang, Y., Rowland, R.R., Lawson, S.R., Christopher-Hennings, J., Yoon, K.J., Nelson, E.A., The 2b protein as a minor structural component of PRRSV. Virus Res. 2005, 114(1-2): 177-81. PMID: 16095746

Rowland, R.R., Chauhan, V., Fang, Y., Pekosz, A., Kerrigan, M., Burton, M.D., Intracellular localization of the severe acute respiratory syndrome coronavirus nucleocapsid protein: absence of nucleolar accumulation during infection and after expression as a recombinant protein in vero cells. J. Virol. 2005, 79: 11507-11512. PMID: 16103202 http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16103202

Plagemann, P.G.W., Rowland, R.R.R., Cafruny, W.A., Polyclonal Hypergammaglobulinemia and formation of hydrophobic immune complexes in porcine reproductive and respiratory syndrome virus-infected and uninfected pigs. Viral Immunol. 2005, 18(1): 138-47. PMID: 15802958

Agbas, A., Zaidi, A., Michaelis, E.K., Decreased activity and increased aggregation of brain calcineurin during aging. Brain Res. 2005, 1059: 59-71. PMID: 16150427

Lushington, G.H., Zaidi, A., Michaelis, M.L., Theoretically predicted structures of plasma membrane Ca2+-ATPase and their susceptibilities to oxidation. J. Mol. Graph. Model. 2005, 24: 175-185. PMID: 16169758

Osborn, K.D., Zaidi, A., Urbauer, R.J.B., Michaelis, M.L., Johnson, C.K., Single molecule characterization of the dynamics of calmodulin bound tooxidatively modified plasma membrane Ca2+ ATPase. Biochemistry 2005, 44: 11074 81. PMID: 16101291

Alterman, M.A., Kornilayev, B., Duzhak, T., Yakovlev, D., Quantitative analysis of cytochrome p450 isozymes by means of uniqueisozyme specific tryptic peptides: a proteomic approach. Drug Metab. Dispos. 2005, 33: 1399 407. PMID: 15951447 http://dmd.aspetjournals.org/cgi/reprint/33/9/1399

Zaidi, A., Jiang, L., Michaelis, M.L., Age related alterations in Ca2+ regulatory proteins localized in neuronal raft microdomains. Free Radic. Biol. Med. 2005, 39: S132-3 [366].

Esch, S.W., Zaidi, A., Williams, T.D., Age related changes in rat brain sphingolipid profile by ESI MS/MS. Proc. Amer. Soc. Mass Spec. 2005, AO52889.

Gokulrangan, G., Kanski, J., Zaidi, A., Schoneich, C., Proteomic analysis of age related protein nitration in rat cerebellum. AAPS Journal 2005, 7(S2): M1102.

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2004

Clevenger, R.C., Blagg, B.S., Design, synthesis, and evaluation of a radicicol and geldanamycin chimera, radamide. Org. Lett. 2004, 6(24): 4459-62. PMID: 15548050

Shen, G., Yu, X.M., Blagg, B.S., Syntheses of photolabile novobiocin analogues. Bioorg. Med. Chem. Lett. 2004, 14(23): 5903-6. PMID: 15501066

Yu, X.M., Shen, G., Blagg, B.S.J., Synthesis of (-)-noviose from 2,3-O-isopropylidene-D-erythronolactol. J. Org. Chem. 2004, 69(21): 7375-8. PMID: 15471498

Clevenger, R.C., Raibel, J.M., Peck, A.M., Blagg, B.S.J., Biotinylated geldanamycin. J. Org. Chem. 2004, 69(13): 4375-80. PMID: 15202892

Bousfield, G.R., Butnev, V.Y., Nguyen, V.T., Gray, C.M., Dias, J.A., MacColl, R., Eisele, L., Harvey, D.J., Differential effects of alpha subunit Asparagine56 oligosaccharide structure on equine lutropin and follitropin hybrid conformation and receptor-binding activity. Biochemistry 2004, 43(33): 10817-33. PMID: 15311943

Jiang, H., Butnev, V.Y., Bousfield, G.R., Desaire, H., Glycoprotein profiling by electrospray mass spectrometry. J. Am. Soc. Mass Spectrom. 2004, 15: 750-758. PMID: 15121204

Wickstrum, J.R., Egan, S.M., Amino acid contacts between sigma 70 domain 4 and the transcription activators RhaS and RhaR. J. Bacteriol. 2004, 186(18): 6277-85. PMID: 15342598

Berring, E., Brancato, S., Grant, K., Schaper, E., Kadavil, S., Smagin, H., Hatic II, S.O., Picking, W.D., Serfis, A., Destabilization of phospholipid model membranes by YplA, a phospholipase A2 secreted by Yersinia enterocolitica. Chem. Phys. Lipids 2004, 131: 135-149. PMID: 15351266

Brobst, D.E., Ding, X., Creech, K.L., Goodwin, B., Kelley, B., Staudinger, J.L., Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. J. Pharmacol. Exp. Ther. 2004, 310(2): 528-35. PMID: 15075359

Anakk, S., Kalsotra, A., Kikuta, Y., Huang, W., Zhang, J., Staudinger, J.L., Moore, D.D., Strobel, H.W., CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11, Pharmacogenomics J. 2004, 4(2): 91-101. PMID: 14770174

Zhao, Z., Gruszczynska-Biegala, J., Cheuvront, T., Yi, H., von der Mark, H., von der Mark, K., Kaufman, S.J., Zolkiewska, A., Interaction of the disintegrin and cysteine-rich domains of ADAM12 with integrin? a7b1. Exp. Cell Res. 2004, 298: 28-37. PMID: 15242759

Ye, Q., Xie, S., Huang, M., Huang, W., Lu, J., Ma, Z., Metalloform-selective inhibitors of E. coli methionine aminopeptidase and X-ray structure of a Mn(II)-form enzyme complexed with an inhibitor. J. Am. Chem. Soc. 2004, 126: 13940-1. PMID: 15506752

Allen, M.A., Urbauer, R.J. B., Zaidi, A., Williams, T., Urbauer, J.L., Johnson, C.K., Fluorescence labeling, purification, and immobilization of a double cysteine mutant calmodulin fusion protein for single-molecule experiments. Anal. Biochem. 2004, 325: 273-284. PMID: 14751262

Osborn, K.D., Zaidi, A., Mandal, A., Urbauer, R.J.B., Johnson, C.K., Single-molecule dynamics of the calcium-dependent activation of plasma-membrane Ca2+-ATPase by calmodulin. Biophysical J. 2004, 87: 1892-1899. PMID: 15446271 http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=15446271

Dremina, E.S., Sharov, V.S., Kumar, K., Zaidi, A., Michaelis, E.K., Schöneich, C., Antiapoptotic protein Bcl-2 interacts with and destabilizes the sarco/endoplasmic reticulum Ca-ATPase (SERCA). Biochem. J. 2004, 383: 361-370. PMID: 15245329

Osborn, K.D., Bartlett, R.K., Mandal, A., Zaidi, A., Urbauer, R.J.B., Urbauer, J.L., Galeva, N., Williams, T.D., Johnson, C.K., Single-molecule dynamics reveal an altered conformation for the autoinhibitory domain of plasma membrane Ca2+-ATPase bound to oxidatively modified calmodulin. Biochemistry 2004, 43: 12937-12944. PMID: 15461467

Michaelis, M.L., Zaidi, A., Ansar, S., Dobrowsky, R., Age-dependent up-regulation of brain acid-sphingomyelinase in F344/BNF1 rats. Program No. 1017.11. 2004 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, October 2004.

Zaidi, A., Cokulrangan, G., Kanski, J., Michaelis, M.L., Schoneich, C., Proteomic strategies in analysis of age-dependent oxidative modifications in brain proteins. Abstract 28.21. ASBMB Annual Meeting and 8th IUBMB Conference, FASEB J. June 2004.

Zaidi, A., Osborn, K., Urbauer, R., Michaelis, M.L., Johnson, C., Single molecule dynamics of the Calmodulin binding domain of oxidatively modified plasma membrane Ca2+-ATPase. Abstract 326. Free Radic. Biol. Med. 2004, 37(1): S112.

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2003

Nguyen, V.T., Singh, V., Butnev, V.Y., Gray, C.M., Westfall, S., Davis, J.S., Dias, J.A., Bousfield, G.R., Inositol phosphate stimulation by LH requires the entire alpha Asn56 oligosaccharide. Mol. Cell. Endocrinol. 2003, 199(1-2): 73-86. PMID: 12581881

Harrington, A.T., Hearn, P.D., Picking, W.L., Barker, J.R., Wessel A., Picking, W.D., Structural characterization of the N-terminus of IpaC from Shigella flexneri. Infect. Immun. 2003, 71: 1255-1264. PMID: 12595440

Anakk, S., Kalsotra, A., Shen, Q., Vu, M.T., Staudinger, J.L., Davies, P.J., Strobel, H.W., Genomic characterization and regulation of CYP3a13: Role of xenobiotics and nuclear receptors. FASEB J. 2003, 17(12): 1736-8. PMID: 12958193

Staudinger, J.L., Madan, A., Carol, K.M., Parkinson, A., Regulation of drug transporter gene expression by nuclear receptors. Drug Metab. Dispos. 2003, 31(5): 523-7. PMID: 12695338

Cao, Y., Zhao, Z., Gruszczynska-Biegala, J., Zolkiewska, A., Role of metalloprotease disintegrin ADAM12 in determination of quiescent reserve cells during myogenic differentiation in vitro. Mol. Cel. Biol. 2003, 23: 6725-6738. PMID: 12972593 http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12972593

Galeva, N., Yakovlev, D., Duzhak, T., Koen, Y.A., Alterman, M.A., Direct identification of cytochrome P250 isozymes by MALDI-TOF based protomic approach. Drug. Metab. Dispos. 2003, 31: 351-355. PMID: 12642458 http://dmd.aspetjournals.org/cgi/reprint/31/4/351

Duzhak, T., Emerson, M.R., Chakrabarty, A., Alterman, M.A., LeVine, S.M., Analysis of protein induction in the CNS of SJL mice with experimental allergic encephalomyelitis by proteomic screening and immunohistochemistry. Cell Mol. Biol. 2003, 49(5): 723-32. PMID: 14528908

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Selected COBRE-PSF Presentations, 2002-June 2006

Brian Blagg
Nine invited presentations including:

COBRE

Copyright © 2012
Center for Biomedical Research Excellence in Protein Structure and Function
Department of Medicinal Chemistry, School of Pharmacy
The University of Kansas

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