Biomolecular NMR Laboratory

Publications

Dey, S., Anbanandam, A., Mumford, B.E., De Guzman, R.N. (2017) Characterization of Small-Molecule Scaffolds That Bind to the Shigella Type III Secretion System Protein IpaD. ChemMedChem. 12(18):1534-1541. doi: 10.1002/cmdc.201700348. Epub 2017 Aug 31. PMID: 28750143

Kaur, K., Park, H., Pandey, N., Azuma, Y., De Guzman, R.N. (2017) Identification of a new small ubiquitin-like modifier (SUMO)-interacting motif in the E3 ligase PIASy. J. Biol. Chem.  292(24):10230-10238. doi: 10.1074/jbc.M117.789982. Epub 2017 Apr 28. PMCID:  PMC5473226  (Biomolecular NMR Core Laboratory listed in acknowledgement)

Budiardjo, S.J., Licknack, T.J., Cory, M.B., Kapros, D., Roy, A., Lovell, S., Douglas, J., Karanicolas, J.  (2016) Full and Partial Agonism of a Designed Enzyme Switch. ACS Synth. Biol. 2016 Dec 16;5(12):1475-1484. Epub 2016 Jul 22. PMCID: PMC5161622

Gowthaman, R., Miller, S.A., Rogers, S., Khowsathit, J., Lan, L., Bai, N., Johnson, D.K., Liu, C., Xu, L., Anbanandam, A., Aubé, J., Roy, A., Karanicolas, J. (2016)  DARC: Mapping surface topography by ray-casting for effective virtual screening at protein interaction sites. J. Med. Chem. 59(9):4152-70. PMID:  26126123.  PMC4707132 [Available on 2017-05-12]

McShan, A.C., Anbanandam, A., Patnaik, S., De Guzman, R.N. (2016) Characterization of the binding of Hydroxyindole, Indoleacetic acid, and Morpholinoaniline to the Salmonella Type III secretion system proteins SipD and SipB. ChemMedChem. 11(9):963-71. PMCID: PMC5010876

Alaofi, A., Farokhi, E., Prasasty, V.D., Anbanandam, A., Kuczera, K., Siahaan, T.J. (2016) Probing the interaction between cHAVc3 peptide and the EC1 domain of E-cadherin using NMR and molecular dynamics simulations. J. Biomol. Struct. Dyn. 12:1-13.  PMCID: PMC5061580

Lan, L., Appelman, C., Smith, A.R., Yu, J., Larsen, S., Marquez, R.T., Liu, H., Wu, X., Gao, P., Roy, A., Anbanandam, A., Gowthaman, R., Karanicolas, J., De Guzman, R.N., Rogers, S., Aubé, J., Ji, M., Cohen, R.S., Neufeld, K.L., Xu, L. (2015) Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol. Oncol. 9(7):1406-20. PMC4523432

Awasthi, S., Anbanandam, A., Rodgers, K.K. (2015) Structure of a TLR4-interacting SPA4 peptide. RSC Adv. 5(35):27431-27438. PMC4392768

Barta, M.L., Hickey, J.M., Anbanandam, A., Dyer, K., Hammel, M., Hefty, P.S. (2014) Atypical Response Regulator ChxR from Chlamydia trachomatis Is Structurally Poised for DNA Binding. PLoS One. 9(3):e91760.  PMCID:  PMC3960148.

Prasasty VD, Krause ME, Tambunan US, Anbanandam A, Laurence JS, Siahaan TJ. (2014) 1H, 13C and 15N backbone assignment of the EC-1 domain of human E-cadherin. Biomol. NMR Assign. 2014 Feb 8. [Epub ahead of print]  PMCID: PMC4133310.

Takahashi D, Hiromasa Y, Kim Y, Anbanandam A, Yao X, Chang KO, Prakash O. (2013) Structural and dynamics characterization of norovirus protease. Protein Sci. 22(3):347-57. PMCID: PMC3595464.

Sarma, A.V., Anbanandam, A., Kelm, A., Mehra-Chaudhary, R., Wei, Y., Qin, P., Lee, Y., Berjanskii, M.V., Mick, J.A., Beamer, L.J., Van Doren, S.R. (2012) Solution NMR of a 463-residue phosphohexomutase: domain 4 mobility, substates, and phosphoryl transfer defect. Biochemistry 51(3):807-19.  PMCID: PMC3448444

Fernando Estrada, D., De Guzman, R. N. (2011) Structural Characterization of the Crimean-Congo Hemorrhagic Fever Virus Gn Tail Provides Insight into Virus Assembly. J. Biol. Chem. 286:21678-21686.  PMCID: PMC3122224  (Biomolecular NMR Core Laboratory listed in acknowledgement)

Fernando Estrada, D., Conner, M.,  St. Jeor, S. C.,  De Guzman, R. N. (2011) The structure of the hantavirus zinc finger domain is conserved and represents the only natively folded region of the Gn cytoplasmic tail. Front. Microbio. 2 (251): 1-8.  (Biomolecular NMR Core Laboratory listed in acknowledgement)

Takahashi, D., Kim, Y., Chang, K.O., Anbanandam, A., Prakash, O. (2011) Backbone and side-chain (1)H, (15)N, and (13)C resonance assignments of Norwalk virus protease. Biomol. NMR Assign. 6(1):19-21. doi: 10.1007/s12104-011-9316-3. Epub 2011 Jun 8. PMCID: PMC4479497

Day, T.P., Sil, D., Shukla, N.M., Anbanandam, A., Day, V.W., David, S.A. (2011) Imbuing aqueous solubility to amphotericin B and nystatin with a vitamin. Mol. Pharm. 8(1):297-301. PMCID: PMC3034802

Chatterjee, S., Zhong, D., Nordhues, BA., Battile, KP., Lovell, S., De Guzman, RN. (2010) The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate. Protein Sci. 20:75-86. PMCID: PMC3047063

Williams, A.S., Lovell, S., Anbanandam, A., El-Chami, R., Bann, J.G. (2009) Domain 4 of the anthrax protective antigen maintains structure and binding to the host receptor CMG2 at low pH. Protein Sci. 18: 2277-2286. PMCID: PMC2788282

Wang Y, Zhang L, Picking WL, Picking WD, De Guzman RN. (2008) Structural dissection of the extracellular moieties of the type III secretion apparatus. Mol. BioSyst. 4, 1176-80.

Wang Y, Boudreaux DM, Estrada DF, Egan CW, St. Jeor SC, De Guzman RN. (2008) NMR structure of the N-terminal coiled coil domain of the Andes hantavirus nucleocapsid protein. J. Biol. Chem. 283, 28297-304. PMID: 18687679.

Nonoyama, A., Laurence, J.S., Garriques, L., Qi, H., Le, T., and Middaugh, C.R. (2008) A biophysical characterization of AC137 and evaluation of the empirical phase diagram using a peptide model. J. Pharm. Sci., 97:2552-67.

Martin, A., David. V., Laurence, J.S., Schwarz, P.M., Lafer, E.M., Hedge, A.M., and Rowe, P.S. (2008) ³Degradation of MEPE, DMP1 & release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP², Endocrinology 149: 1757-1772.

Skinner, A.L. and Laurence, J.S. (2008) High-field Solution NMR Spectroscopy as a tool for Assessing Protein Interactions with Small Molecule Ligands², J. Pharm. Sci. 97: 4670-4695.

Ciaccio, N.A., Moreno, M.L., Bauer, R.L. and Laurence, J.S. (2008) High-Yield Expression in E. coli and Refolding of the bZIP Domain of Activating Transcription Factor 5. Protein Expr. Purif. 62, 235-243.