Biomolecular NMR Laboratory


Gowthaman, R., Miller, S.A., Rogers, S., Khowsathit, J., Lan, L., Bai, N., Johnson, D.K., Liu, C., Xu, L., Anbanandam, A., Aubé, J., Roy, A., Karanicolas, J. (2016)  DARC: Mapping surface topography by ray-casting for effective virtual screening at protein interaction sites. J. Med. Chem. 59(9):4152-70. PMID:  26126123.  PMC4707132 [Available on 2017-05-12]

McShan, A.C., Anbanandam, A., Patnaik, S., De Guzman, R.N. (2016) Characterization of the binding of Hydroxyindole, Indoleacetic acid, and Morpholinoaniline to the Salmonella Type III secretion system proteins SipD and SipB. ChemMedChem. 11(9):963-71. PMID:  26990667 [PubMed - in process]

Alaofi, A., Farokhi, E., Prasasty, V.D., Anbanandam, A., Kuczera, K., Siahaan, T.J. (2016) Probing the interaction between cHAVc3 peptide and the EC1 domain of E-cadherin using NMR and molecular dynamics simulations. J. Biomol. Struct. Dyn. 12:1-13.  PMID: 26728967 [PubMed - as supplied by publisher]

Lan, L., Appelman, C., Smith, A.R., Yu, J., Larsen, S., Marquez, R.T., Liu, H., Wu, X., Gao, P., Roy, A., Anbanandam, A., Gowthaman, R., Karanicolas, J., De Guzman, R.N., Rogers, S., Aubé, J., Ji, M., Cohen, R.S., Neufeld, K.L., Xu, L. (2015) Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol. Oncol. 9(7):1406-20. PMC4523432

Awasthi, S., Anbanandam, A., Rodgers, K.K. (2015) Structure of a TLR4-interacting SPA4 peptide. RSC Adv. 5(35):27431-27438. PMC4392768

Barta, M.L., Hickey, J.M., Anbanandam, A., Dyer, K., Hammel, M., Hefty, P.S. (2014) Atypical Response Regulator ChxR from Chlamydia trachomatis Is Structurally Poised for DNA Binding. PLoS One. 9(3):e91760. PMID: 24646934 PMCID:  PMC3960148.

Prasasty VD, Krause ME, Tambunan US, Anbanandam A, Laurence JS, Siahaan TJ. (2014) 1H, 13C and 15N backbone assignment of the EC-1 domain of human E-cadherin. Biomol. NMR Assign. 2014 Feb 8. [Epub ahead of print] PMID: 24510398  PMCID: PMC4133310.

Takahashi D, Hiromasa Y, Kim Y, Anbanandam A, Yao X, Chang KO, Prakash O. (2013) Structural and dynamics characterization of norovirus protease. Protein Sci. 22(3):347-57. PMID: 23319456  PMCID: PMC3595464.

Rosslyn, G., Fabien, K., Sorgen, P.L. (2012)1H, 13C, and 15N backbone resonance assignments of the connexin43 carboxyl terminal domain attached to the 4th transmembrane domain in detergent micelles. Biomol NMR Assign. 2012, October 13, 2012. [Epub ahead of print]

Sarma, A.V., Anbanandam, A., Kelm, A., Mehra-Chaudhary, R., Wei, Y., Qin, P., Lee, Y., Berjanskii, M.V., Mick, J.A., Beamer, L.J., Van Doren, S.R. (2012) Solution NMR of a 463-residue phosphohexomutase: domain 4 mobility, substates, and phosphoryl transfer defect. Biochemistry 51(3):807-19.

Fernando Estrada, D., De Guzman, R. N. (2011) Structural Characterization of the Crimean-Congo Hemorrhagic Fever Virus Gn Tail Provides Insight into Virus Assembly. J. Biol. Chem. 286:21678-21686.

Fernando Estrada, D., Conner, M.,  St. Jeor, S. C.,  De Guzman, R. N. (2011) The structure of the hantavirus zinc finger domain is conserved and represents the only natively folded region of the Gn cytoplasmic tail. Front. Microbio. 2, 251, 1-8.

Chatterjee, S., Zhong, D., Nordhues, BA., Battile, KP.,Lovell, S., De Guzman, RN. (2011) The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate. Protein Sci. 20:75-86.

Takahashi, D., Kim, Y., Chang, K.O., Anbanandam, A., Prakash, O. (2011) Backbone and side-chain (1)H, (15)N, and (13)C resonance assignments of Norwalk virus protease. Biomol. NMR Assign. Jun 8.

Day, T.P., Sil, D., Shukla, N.M., Anbanandam, A., Day, V.W., David, S.A. (2011) Imbuing aqueous solubility to amphotericin B and nystatin with a vitamin. Mol. Pharm. 8(1):297-301.

Williams, A.S., Lovell, S., Anbanandam, A., El-Chami, R., Bann, J.G. (2009) Domain 4 of the anthrax protective antigen maintains structure and binding to the host receptor CMG2 at low pH. Protein Sci. 18: 2277-2286.

Wang Y, Zhang L, Picking WL, Picking WD, De Guzman RN. (2008) Structural dissection of the extracellular moieties of the type III secretion apparatus. Mol. BioSyst. 4, 1176-80.

Wang Y, Boudreaux DM, Estrada DF, Egan CW, St. Jeor SC, De Guzman RN. (2008) NMR structure of the N-terminal coiled coil domain of the Andes hantavirus nucleocapsid protein. J. Biol. Chem. 283, 28297-304. PMID: 18687679.

Nonoyama, A., Laurence, J.S., Garriques, L., Qi, H., Le, T., and Middaugh, C.R. (2008) A biophysical characterization of AC137 and evaluation of the empirical phase diagram using a peptide model. J. Pharm. Sci., 97:2552-67.

Martin, A., David. V., Laurence, J.S., Schwarz, P.M., Lafer, E.M., Hedge, A.M., and Rowe, P.S. (2008) ³Degradation of MEPE, DMP1 & release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP², Endocrinology 149: 1757-1772.

Skinner, A.L. and Laurence, J.S. (2008) High-field Solution NMR Spectroscopy as a tool for Assessing Protein Interactions with Small Molecule Ligands², J. Pharm. Sci. 97: 4670-4695.

Ciaccio, N.A., Moreno, M.L., Bauer, R.L. and Laurence, J.S. (2008) High-Yield Expression in E. coli and Refolding of the bZIP Domain of Activating Transcription Factor 5. Protein Expr. Purif. 62, 235-243.