Protein Production Group


Lan, L., Xing, M., Douglas J.T., Gao, P., Hanzlik R.P., Xu, L. (2017)  Human oncoprotein Musashi-2 N-terminal RNA recognition motif backbone assignment and identification of RNA-binding pocket. Oncotarget 8(63):106587-106597.  PMID:  29290973  PMCID:  PMC573975

Yu, J., Lan, L., Lewin, S.J., Rogers, S.A., Roy, A., Wu, X., Gao, P., Karanicolas, J., Aubé, J., Sun, B., Xu, L. (2017)  Identification of novel small molecule Beclin 1 mimetics activating autophagy.  Oncotarget  8(31):51355-51369. doi: 10.18632/oncotarget.17977. eCollection 2017 Aug 1. PMCID: PMC5584254

Obayashi, E., Luna, R.E., Nagata, T., Martin-Marcos, P., Hiraishi, H., Singh, C.R., Erzberger, J.P., Zhang, F., Arthanari, H., Morris, J., Pellarin, R., Moore, C., Harmon, I., Papadopoulos, E., Yoshida, H., Nasr, M.L., Unzai, S., Thompson, B., Aubé, E., Hustak, S., Stengel, F., Dagraca, E., Ananbandam, A., Gao, P., Urano, T., Hinnebusch, A.G., Wagner, G., Asano, K. (2017) Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.  Cell Rep. 18(11):2651-2663. doi: 10.1016/j.celrep.2017.02.052.  PMCID: PMC5382721

McNiff, M.L., Haynes, E.P., Dixit, N., Gao, F.P., Laurence, J.S. (2016) Thioredoxin fusion construct enables high-yield production of soluble, active matrix metalloproteinase-8 (MMP-8) in Escherichia coli. Protein Expr. Purif. 122:64-71.  PMCID: PMC5137367

Wahome, N., Cooper, A., Thapa, P., Choudhari, S., Gao, F.P., Volkin, D.B., Middaugh, C.R. (2016) Production of well-characterized virus-like particles in an Escherichia coli-based expression platform for preclinical vaccine assessments. Methods Mol. Biol. 1404:437-57. PMID: 27076315  [PubMed - in process]

Lan, L., Appelman, C., Smith, A.R., Yu, J., Larsen, S., Marquez, R.T., Liu, H., Wu, X., Gao, P., Roy, A., Anbanandam, A., Gowthaman, R., Karanicolas, J., De Guzman, R.N., Rogers, S., Aubé, J., Ji, M., Cohen, R.S., Neufeld, K.L., Xu, L. (2015) Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol. Oncol. 2015 Aug;9(7):1406-20. doi: 10.1016/j.molonc.2015.03.014. Epub 2015 Apr 10.  PMCID: PMC4523432

Chen, C., Shrestha, R., Jia, K., Gao, P.F., Geisbrecht, B.V., Bossmann, S.H., Shi, J., Li, P. (2015) Characterization of Dye-decolorizing Peroxidase (DyP) from Thermomonospora curvata Reveals Unique Catalytic Properties of A-type DyPs. J. Biol. Chem. 290(38):23447-63. PMCID: PMC4645587

Wu, X., Lan, L., Wilson, D.M., Marquez, R.T., Tsao, W.C., Gao, P., Roy, A., Turner, B.A., McDonald, P., Tunge, J.A., Rogers, S.A., Dixon, D.A., Aubé, J., Xu, L.(2015) Identification and validation of novel small molecule disruptors of HuR-mRNA interaction. ACS Chem. Biol. 10(6):1476-84.  PMCID: PMC4631057

Murray, D.T., Li, C., Gao, F.P., Qin, H., Cross, T.A., (2014) Membrane protein structural validation by oriented sample solid-state NMR: diacylglycerol kinase.  Biophys. J. 106(8):1559-69.  PMCID: PMC4008839

Thomas, J.C., O’Hara, J.M., Hu, L., Gao, F.P., Joshi, S.B., Volkin, D.B., Brey, R.N., Fang, J., Karanicolas, J.*, Mantis, N.J., Middaugh, C.R. (2013) Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen. Hum. Vaccin. Immunother. 9(4): 1-9.  PMCID: PMC3903890